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It seemed as though Marcelino was resting players on Sunday against Atleti, and he certainly was doing some of that, but the performances of some of the players who stepped into those roles were awfully good. Antonio Rukavina was the Mahon 5 stars man of the match; Eric Bailly wasn't far behind and in fact as I write this leads our poll for man of the match.
So, what do we know? Areola in goal for sure; rested Mateo Musacchio and Victor Ruiz as the central defense pairing; Mario Gaspar at right back; Bruno Soriano (and, I am pretty sure, Manu Trigueros) in the doble pivote; Denis Suarez on the left wing; Roberto Soldado as one of the two strikers. That's 8 of the 11.
The remaining positions are left back, right wing and second striker. Jaume Costa's injury might keep him out--if not, he's rested. But maybe Eric Bailly goes there again? And Rukavina on right wing? We'll just have to see.
Napoli were only able to draw 1-1 with AC Milan, failing to take advantage of Juventus's away draw at Bologna. They played pretty much their first team; I would not think physical fatigue would be a factor, but mental fatigue and disappointment could be.
Of course, Napoli have to go all out for a win, and a win by two goals in either normal or extra time. Villarreal tend to like to play on the road against teams who have to go forward, because that opens up space for our conterattacks. As Marcelino said, we go into this having the advantage, but it's only about 60-40. Endavant!!